Save up -80% on Cevimeline
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Evoxac
|price without discount in nearest pharmacy. Price may vary.|
We offer free Evoxac coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Cevimeline every time. What are you waiting for? Claim your prescription drug card now!
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Cevimeline volume of distribution
Cevimeline is rapidly absorbed, reaching peak plasma levels between 11/2 and 2 hours. Food decreases the rate of absorption, and the peak concentration is reduced by 17.3%. Cevimeline is less than 20% protein-bound.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Cevimeline
Cevimeline is a parasympathomimetic and muscarinic agonist, with particular effect on M3 receptors. It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjogren’s syndrome. (Wikipedia)
Cevimeline mechanism of action
Muscarinic agonists such as cevimeline bind and activate the muscarinic M1 and M3 receptors. The M1 receptors are common in secretory glands (exocrine glands such as salivary and sweat glands), and their activation results in an increase in secretion from the secretory glands. The M3 receptors are found on smooth muscles and in many glands which help to stimulate secretion in salivary glands, and their activation generally results in smooth muscle contraction and increased glandular secretions. Therefore, as saliva excretion is increased, the symptoms of dry mouth are relieved.
Dosage forms of Cevimeline
Ranbaxy Pharmaceuticals Inc.
Humans and other mammals
Indication of Cevimeline
For the treatment of symptoms of dry mouth in patients with Sj ouml;gren’s Syndrome.
Toxicity of Cevimeline
Toxicity is characterized by exaggeration of parasympathomimetic effects. These may include headache, visual disturbance, lacrimation, sweating, respiratory distress, GI spasm, nausea, vomiting, diarrhea, atrioventricular block, tachycardia, bradycardia, hypotension, shock, mental confusion, cardiac arrhythmias, and tremors.
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