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Price of Cevimeline
Evoxac 30 mg capsule
* price without discount in nearest pharmacy. Price may vary.
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Cevimeline volume of distribution
* 6 L/kg
What is Cevimeline
Cevimeline is a parasympathomimetic and muscarinic agonist, with particular effect on M3 receptors. It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjogren’s syndrome. (Wikipedia)
Cevimeline mechanism of action
Muscarinic agonists such as cevimeline bind and activate the muscarinic M1 and M3 receptors. The M1 receptors are common in secretory glands (exocrine glands such as salivary and sweat glands), and their activation results in an increase in secretion from the secretory glands. The M3 receptors are found on smooth muscles and in many glands which help to stimulate secretion in salivary glands, and their activation generally results in smooth muscle contraction and increased glandular secretions. Therefore, as saliva excretion is increased, the symptoms of dry mouth are relieved.
Dosage forms of Cevimeline
Ranbaxy Pharmaceuticals Inc.
Humans and other mammals
Indication of Cevimeline
For the treatment of symptoms of dry mouth in patients with Sj ouml;gren’s Syndrome.
Toxicity of Cevimeline
Disclaimer: before buying a Cevimeline on prescription, consult your health care provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.