Save up -80% on Chlorambucil

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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Chlorambucil

Leukeran 2 mg tablet



* price without discount in nearest pharmacy. Price may vary.

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Chlorambucil volume of distribution

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What is Chlorambucil

A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)

Chlorambucil mechanism of action

Alkylating agents work by three different mechanisms: 1) attachment of alkyl groups to DNA bases, resulting in the DNA being fragmented by repair enzymes in their attempts to replace the alkylated bases, preventing DNA synthesis and RNA transcription from the affected DNA, 2) DNA damage via the formation of cross-links (bonds between atoms in the DNA) which prevents DNA from being separated for synthesis or transcription, and 3) the induction of mispairing of the nucleotides leading to mutations.

Dosage forms of Chlorambucil

Tabletoral2 mg
Tablet, film coatedoral2 mg/1
Prescription Generics


International Brands



4-(P-Bis(beta-chloroethyl)aminophenyl)butyric acid 4-(p-bis(-chloroethyl)aminophenyl)butyric acid


Aspen Global Inc.

CAS number






Affected organisms

Humans and other mammals

Indication of Chlorambucil

For treatment of chronic lymphatic (lymphocytic) leukemia, childhood minimal-change nephrotic syndrome, and malignant lymphomas including lymphosarcoma, giant follicular lymphoma, Hodgkin’s disease, non-Hodgkin’s lymphomas, and Waldenstroms Macroglobulinemia.

Toxicity of Chlorambucil

RX24 Drugs Disclaimer: before buying a Chlorambucil on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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