Save up -80% on Chlorhexidine
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Paroex
|$8.48||1 bottle (473ml) 0.12% rinse|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Paroex coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Chlorhexidine every time. What are you waiting for? Claim your prescription drug card now!
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Chlorhexidine volume of distribution
The percutaneous absorption of chlorhexidine gluconate (chlorhexidine digluconate; Hibitane) through hairless rat skin with or without stratum corneum was studied. For tests carried out on whole skin, storage in cutaneous structures after 48 hr was more important than diffusion; the reverse was observed for stripped skin. When the skin was stripped, the amount absorbed was multiplied by approximately 100, and the amount stored in skin by approximately 10. The difference in chlorhexidine diffusion observed between whole and stripped skin was related to the physicochemical characteristics of chlorhexidine.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Chlorhexidine
A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
Chlorhexidine mechanism of action
Chlorhexidine’s antimicrobial effects are associated with the attractions between chlorhexidine (cation) and negatively charged bacterial cells. After chlorhexidine is absorpted onto the organism’s cell wall, it disrupts the integrity of the cell membrane and causes the leakage of intracellular components of the organisms.
Dosage forms of Chlorhexidine
|Chlorhexidine Gluconate||20/20mg||250mL Shampoo||$31.00|
1,1′-Hexamethylene bis(5-(P-chlorophenyl)biguanide) Chlorhexidin
3 M Health Care
Indication of Chlorhexidine
For reduction of pocket depth in patients with adult periodontitis, used as an adjunct to scaling and root planing procedures. Also for prevention of dental caries, oropharyngeal decontamination in critically ill patients, hand hygiene in health-care personnel, general skin cleanser, and catheter site preparation and care.
Toxicity of Chlorhexidine
LDsub50/sub= 2g/kg (human, oral); LDsub50/sub= 3 g/kg (rat, oral); LDsub50/sub= 2.5 g/kg (mice, oral); LDsub50/sub= 21 mg/kg (male rat, IV); LDsub50/sub= 23 mg/kg (female rat, IV); LDsub50/sub= 25 mg/kg (male mice, IV); LDsub50/sub= 24 mg/kg (female mice, IV); LDsub50/sub= 1g/kg (rat, subcutaneous); LDsub50/sub= 637 mg/kg (male mice, subcutaneous); LDsub50/sub= 632 mg/kg (female mice, subcutaneous)
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