Save up -80% on Chlorzoxazone

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Chlorzoxazone

Parafon forte dsc 500 mg caplet

$2.65

caplet

* price without discount in nearest pharmacy. Price may vary.

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Chlorzoxazone volume of distribution

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What is Chlorzoxazone

A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)

Chlorzoxazone mechanism of action

Chlorzoxazone inhibits degranulation of mast cells, subsequently preventing the release of histamine and slow-reacting substance of anaphylaxis (SRS-A), mediators of type I allergic reactions. Chlorzoxazone also may reduce the release of inflammatory leukotrienes. Chlorzoxazone may act by inhibiting calcium and potassium influx which would lead to neuronal inhibition and muscle relaxation. Data available from animal experiments as well as human study indicate that chlorzoxazone acts primarily at the level of the spinal cord and subcortical areas of the brain where it inhibits multisynaptic reflex arcs involved in producing and maintaining skeletal muscle spasm

Dosage forms of Chlorzoxazone

FormRouteStrength
Tabletoral
Tabletocclusive dressing technique500 mg/1
Tabletoral250 mg/1
Prescription Generics

false

International Brands

Acetazone Forte

Synonyms

2-hydroxy-5-chlorobenzoxazole 5-chloro-2-Benzoxazolinone

Manufacturers

Teva Canada Limited

CAS number

95-25-0

UNII

H0DE420U8G

State

solid

Affected organisms

Humans and other mammals

Indication of Chlorzoxazone

For the relief of discomfort associated with acute painful musculoskeletal conditions.

Toxicity of Chlorzoxazone

Oral, mouse: LD sub 50 /sub = 440 mg/kg; Oral, rat: LD sub 50 /sub = 763 mg/kg; Symptoms of overdose include diarrhea, dizziness, drowsiness, headache, light-headedness, nausea, and vomiting.

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