Save up -80% on Chlorzoxazone

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Parafon Forte

$288.5530 tablets/250mg
price without discount in nearest pharmacy. Price may vary.

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We offer free Parafon Forte coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Chlorzoxazone every time. What are you waiting for? Claim your prescription drug card now!

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Chlorzoxazone volume of distribution

Oral clearance (Cl) and volume of distribution (Vd) of CHZ was found to be 15.77 +/- 4.81 (L/hr) and 33.13 +/- 9.75 L, respectively. CONCLUSION: An oral dose of 400 mg CHZ was used to probe for the pharmacokinetic characteristics of this drug in Thai volunteers.

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2018 Statistics

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What is Chlorzoxazone

A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)

Chlorzoxazone mechanism of action

Chlorzoxazone inhibits degranulation of mast cells, subsequently preventing the release of histamine and slow-reacting substance of anaphylaxis (SRS-A), mediators of type I allergic reactions. Chlorzoxazone also may reduce the release of inflammatory leukotrienes. Chlorzoxazone may act by inhibiting calcium and potassium influx which would lead to neuronal inhibition and muscle relaxation. Data available from animal experiments as well as human study indicate that chlorzoxazone acts primarily at the level of the spinal cord and subcortical areas of the brain where it inhibits multisynaptic reflex arcs involved in producing and maintaining skeletal muscle spasm

Dosage forms of Chlorzoxazone

Tabletocclusive dressing technique500 mg/1
Tabletoral250 mg/1

Prescription Generics


International Brands

Acetazone Forte


2-hydroxy-5-chlorobenzoxazole 5-chloro-2-Benzoxazolinone


Teva Canada Limited

CAS number






Affected organisms

Humans and other mammals

Indication of Chlorzoxazone

For the relief of discomfort associated with acute painful musculoskeletal conditions.

Toxicity of Chlorzoxazone

Oral, mouse: LD sub 50 /sub = 440 mg/kg; Oral, rat: LD sub 50 /sub = 763 mg/kg; Symptoms of overdose include diarrhea, dizziness, drowsiness, headache, light-headedness, nausea, and vomiting.

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