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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Questran

$42.411 can (378g) 4g/dose powder
Price with discount in nearest pharmacy. Price may vary.

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Cholestyramine volume of distribution

The volume of distribution parameters (Vdss and Vd(area)) did not change following either treatment. The changes in the pharmacokinetic parameters are compatible with an acceleration of ibuprofen elimination induced by oral administration of cholestyramine and not by colestipol. This effect is thought to be due to augmentation of net biliary excretion through enteric binding.

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2018 Statistics

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Total savings $4,735,080

What is Cholestyramine

Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water.

Cholestyramine mechanism of action

Cholestyramine binds bile in the gastrointestinal tract to prevent its reabsorption. The resin is a strong anion exchange resin, which means that it can exchange its chloride anions with anionic bile acids in the gastrointestinal tract and bind them strongly in the resin matrix. The functional group of the anion exchange resin is a quaternary ammonium group attached to an inert styrene-divinylbenzene copolymer.

Dosage forms of Cholestyramine

Package; powderoral4 g
Powder, for suspensionoral4 g/5g
Powder, for suspensionoral4 g/9g

Prescription Generics


International Brands

Alti-cholestyramine Light


Cholestyramine resin Colestyramine


Altimed Pharma Inc.

CAS number






Affected organisms

Humans and other mammals

Indication of Cholestyramine

Indicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia (elevated low density lipoprotein[LDL]cholesterol) who do not respond adequately to diet. Also for the relief of pruritus associated with partial biliary obstruction.

Toxicity of Cholestyramine

Overdose may result in blockage of intestine or stomach.

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