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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Ciclesonide

Omnaris 50 mcg nasal spray

$11.01

g

* price without discount in nearest pharmacy. Price may vary.

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Ciclesonide volume of distribution

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What is Ciclesonide

Ciclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco.

Ciclesonide mechanism of action

Glucocorticoids such as ciclesonide can inhibit leukocyte infiltration at the site of inflammation, interfere with mediators of inflammatory response, and suppress humoral immune responses. The antiinflammatory actions of glucocorticoids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes. Ciclesonide reduces inflammatory reaction by limiting the capillary dilatation and permeability of the vascular structures. These compounds restrict the accumulation of polymorphonuclear leukocytes and macrophages and reduce the release of vasoactive kinins. Recent research suggests that corticosteroids may inhibit the release of arachidonic acid from phospholipids, thereby reducing the formation of prostaglandins. Ciclesonide is a glucocorticoid receptor agonist. On binding, the corticoreceptor-ligand complex translocates itself into the cell nucleus, where it binds to many glucocorticoid response elements (GRE) in the promoter region of the target genes. The DNA bound receptor then interacts with basic transcription factors, causing an increase or decrease in expression of specific target genes, including suppression of IL2 (interleukin 2) expression.

Dosage forms of Ciclesonide

DrugDosageQuantityPrice
Alvesco100mcg120doses Inhaler$90.10
Alvesco160mcg60doses Inhaler$61.00
Alvesco200mcg120doses Inhaler$122.00
Zetonna Nasal Aerosol37mcg60doses Inhaler$301.00
Prescription Generics

false

International Brands

Alvesco

Synonyms

Manufacturers

Takeda Canada Inc

CAS number

126544-47-6

UNII

S59502J185

State

solid

Affected organisms

Humans and other mammals

Indication of Ciclesonide

For the treatment of nasal symptoms associated with seasonal and perennial allergic rhinitis in adults and adolescents 12 years of age and older.

Toxicity of Ciclesonide

RX24 Drugs Disclaimer: before buying a Ciclesonide on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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