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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Cidofovir

Vistide 75 mg/ml vial

$205.71

ml

* price without discount in nearest pharmacy. Price may vary.

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Cidofovir volume of distribution

* 537 126 mL/kg (VISTIDE ADMINISTERED WITHOUT PROBENECID) * 410 102 mL/kg (VISTIDE ADMINISTERED WITH PROBENECID)

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What is Cidofovir

Cidofovir is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses CMV replication by selective inhibition of viral DNA synthesis. (Wikipedia)

Cidofovir mechanism of action

Cidofovir acts through the selective inhibition of viral DNA polymerase.Biochemical data support selective inhibition of CMV DNA polymerase by cidofovir diphosphate, the active intracellular metabolite of cidofovir. Cidofovir diphosphate inhibits herpesvirus polymerases at concentrations that are 8- to 600-fold lower than those needed to inhibit human cellular DNA polymerase alpha, beta, and gamma(1,2,3). Incorporation of cidofovir into the growing viral DNA chain results in reductions in the rate of viral DNA synthesis.

Dosage forms of Cidofovir

FormRouteStrength
Injection, solutionintravenous75 mg/mL
Injection, solutionintravenous375 mg/5mL
Concentrate for solution for infusionIntravenous use75 mg/ml
Prescription Generics

true

International Brands

Cidofovir

Synonyms

({((S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl)oxy}methyl)phosphonic acid (S)-(3-(4-amino-2-Oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid

Manufacturers

Mylan Institutional LLC

CAS number

113852-37-2

UNII

768M1V522C

State

solid

Affected organisms

Human Immunodeficiency Virus

Indication of Cidofovir

For the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS)

Toxicity of Cidofovir

Kidney damage, fall in the number of white blood cells, decreased platelets

RX24 Drugs Disclaimer: before buying a Cidofovir on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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