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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Cilazapril

Apo-Cilazapril 1 mg Tablet

$0.39

tablet

* price without discount in nearest pharmacy. Price may vary.

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What is Cilazapril

Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries, among many other names. None of these varieties are available in the United States.

Cilazapril mechanism of action

Cilazapril is a pyridazine ACE inhibitor. It competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. As angiotensin II is a vasoconstrictor and a negative feedback mediator for renin activity, lower angiotensin II levels results in a decrease in blood pressure, an increase in renin activity, and stimulation of baroreceptor reflex mechanisms. Kininase II, an enzyme which degrades the vasodilator bradykinin, is identical to ACE and may also be inhibited.

Dosage forms of Cilazapril

FormRouteStrength
Tabletoral
Tabletoral2.5 mg
Tabletoral5 mg
Prescription Generics

true

International Brands

Apo-cilazapril

Synonyms

Cilazapril Cilazapril anhydrous

Manufacturers

Apotex Inc

CAS number

88768-40-5

UNII

8Q9454114Q

State

solid

Affected organisms

Indication of Cilazapril

Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure.

Toxicity of Cilazapril

Limited data are available with regard to overdosage in humans. The most likely manifestations are hypotension, which may be severe, hyperkalaemia, hyponatraemia and renal impairment with metabolic acidosis. Treatment should be mainly symptomatic and supportive.

RX24 Drugs Disclaimer: before buying a Cilazapril on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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