Save up -80% on Cimetidine
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Price of Cimetidine
Tagamet 300 mg tablet
* price without discount in nearest pharmacy. Price may vary.
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Cimetidine volume of distribution
What is Cimetidine
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy. (PubChem)
Cimetidine mechanism of action
Cimetidine binds to an H sub2 /sub-receptor located on the basolateral membrane of the gastric parietal cell, blocking histamine effects. This competitive inhibition results in reduced gastric acid secretion and a reduction in gastric volume and acidity.
Dosage forms of Cimetidine
|Tablet, film coated||oral||200 mg/1|
Humans and other mammals
Indication of Cimetidine
For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion.
Toxicity of Cimetidine
Symptoms of overdose include nausea, vomiting, diarrhea, increased saliva production, difficulty breathing, and a fast heartbeat.
Disclaimer: before buying a Cimetidine on prescription, consult your health care provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.