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Price of Cinchocaine
Dibucaine hcl powder
* price without discount in nearest pharmacy. Price may vary.
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Cinchocaine volume of distribution
What is Cinchocaine
A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
Cinchocaine mechanism of action
Local anesthetics block both the initiation and conduction of nerve impulses by decreasing the neuronal membrane’s permeability to sodium ions through sodium channel inhibition. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.
Dosage forms of Cinchocaine
Cvs Hemorrhoidal Topical Analgesic
CVS Pharmacy, Inc.
Humans and other mammals
Indication of Cinchocaine
For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.
Toxicity of Cinchocaine
Subcutaneous LD sub50 /sub in rat is 27 mg/kg. Symptoms of overdose include convulsions, hypoxia, acidosis, bradycardia, arrhythmias and cardiac arrest.
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