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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Clobazam

Apo-Clobazam 10 mg Tablet

$0.23

tablet

* price without discount in nearest pharmacy. Price may vary.

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Clobazam volume of distribution

Vdss = 100 L. This high volume of distribution suggests extensive distribution to body tissues.

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What is Clobazam

Clobazam belongs to the 1,5-benzodiazepine class of drugs and is expected to have a better side-effect profile compared to older 1,4-benzodiazepines. It has been marketed as an anxiolytic since 1975 and an anticonvulsant since 1984. The oral preparation was FDA approved on October 21, 2011. An oral suspension is expected to be available in 2013.

Clobazam mechanism of action

Clobazam binds at distinct binding sites associated with the chloride ionopore at the post-synaptic GABA receptor. These GABA receptors are in various locations in the CNS (limbic, reticular formation) and clobazam increases the duration of time for which the chloride ionopore is open. As a result, hyper polarization and stabilization of the membrane occur as the post-synaptic inhibitory effect of GABA is enhanced.

Dosage forms of Clobazam

FormRouteStrength
Tabletoral10 mg
Suspensionoral2.5 mg/mL
Tabletoral10 mg/1
Prescription Generics

true

International Brands

Apo-clobazam Tablets

Synonyms

1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo(b)(1,4)diazepine-2,4-dione

Manufacturers

Apotex Inc

CAS number

22316-47-8

UNII

2MRO291B4U

State

solid

Affected organisms

Humans and other mammals

Indication of Clobazam

For treatment and management of epilepsy and seizures associated with Lennox-Gastaut syndrome, a difficult-to-treat form of childhood epilepsy.

Toxicity of Clobazam

The most common adverse effects include somnolence, pyrexia, upper respiratory tract infection, and lethargy.

RX24 Drugs Disclaimer: before buying a Clobazam on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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