Save up -80% on Clotrimazole

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Lotrisone

$63.421 tube (15g) 1%/0.05% cream
Price with discount in nearest pharmacy. Price may vary.

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Clotrimazole volume of distribution

The topical form is minimally absorbed in the serum and tissues. Clotrimazole is a lipophilic drug, and has been shown to be secreted in breastmilk in animal studies. There are limited data available regarding the volume of distribution following oral troche administration.

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2018 Statistics

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Total savings $4,735,080

What is Clotrimazole

An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal cell membranes. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane.

Clotrimazole mechanism of action

Clotrimazole interacts with yeast 14- alpha; demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the membrane. In this way, clotrimazole inhibits ergosterol synthesis, resulting in increased cellular permeability. Clotrimazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms and the uptake of purine, impair triglyceride and/or phospholipid biosynthesis, and inhibit the movement of calcium and potassium ions across the cell membrane by blocking the ion transport pathway known as the Gardos channel.

Dosage forms of Clotrimazole

Canesten 1 Day Vaginal Combipak500mg/1%1pk Cream and Ovules$25.04
Canesten 3 Day Vaginal Cream2%25g Vaginal Cream$22.99
Canesten 6 Day Vaginal Cream1%50g Vaginal Cream$22.99
Canesten Topical Cream1%15g Topical Cream$15.13
Canesten Topical Cream1%30g Topical Cream$19.59
Clotrimazole1%50g Topical Cream (Taro)$25.50
Clotrimazole10mg70 Lozenge$66.00
Lotriderm Cream1%/0.05%15g Cream$43.00
Quadriderm Cream0.025/1/0.5/0.1%5g Cream$17.40
Quadriderm Cream0.025/1/0.5/0.1%10g Cream$26.50

Prescription Generics


International Brands



1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole 1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole


Capital Pharmaceutical, Llc

CAS number






Affected organisms

Yeast and other fungi

Indication of Clotrimazole

For the local treatment of oropharyngeal candidiasis and vaginal yeast infections, also used in fungal infections of the skin such as ringworm, athlete’s foot, and jock itch.

Toxicity of Clotrimazole

Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning, and general irritation of the skin, and cramps.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Clotrimazole on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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