Save up -80% on Clozapine
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Clozaril
|$72.28||90 tablets/100 mg|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Clozapine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Clozapine every time. What are you waiting for? Claim your prescription drug card now!
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Clozapine volume of distribution
Volume of distribution of 1.6 to 7.3 L/kg
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Clozapine
A tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a major adverse effect associated with administration of this agent.
Clozapine mechanism of action
Clozapine’s antipsychotic action is likely mediated through a combination of antogistic effects at D2 receptors in the mesolimbic pathway and 5-HT2A receptors in the frontal cortex. D2 antagonism relieves positive symptoms while 5-HT2A antagonism alleviates negative symptoms.
Dosage forms of Clozapine
|Tablet, orally disintegrating||oral||100 mg/1|
Aa Pharma Inc
Humans and other mammals
Indication of Clozapine
For use in patients with treatment-resistant schizophrenia.
Toxicity of Clozapine
Clozapine carries a black-box warning for agranulocytosis.
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