Save up -80% on Colestipol

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Colestipol

Colestid 5 g Powder Packet

$1.04

packet

* price without discount in nearest pharmacy. Price may vary.

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Colestipol volume of distribution

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What is Colestipol

Highly crosslinked and insoluble basic anion exchange resin used as anticholesteremic. It may also may reduce triglyceride levels.

Colestipol mechanism of action

Colestipol is a non-absorbed, lipid-lowering polymer that binds bile acids in the intestine, impeding their reabsorption. As the bile acid pool becomes depleted, the hepatic enzyme, cholesterol 7-(alpha)-hydroxylase, is upregulated, which increases the conversion of cholesterol to bile acids. This causes an increased demand for cholesterol in the liver cells, resulting in the dual effect of increasing transcription and activity of the cholesterol biosynthetic enzyme, hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase, and increasing the number of hepatic low-density lipoprotein (LDL) receptors. These compensatory effects result in increased clearance of LDL cholesterol (LDL-C) from the blood, resulting in decreased serum LDL-C levels. Serum triglyceride levels may increase or remain unchanged. The end result is increased clearance of LDL-cholesterol from the blood with decreased serum LDL-cholesterol.

Dosage forms of Colestipol

DrugDosageQuantityPrice
Colestid1g120 Tablet$79.00
Colestid Granules5g30 Granules$72.50
Colestid Orange Granules7.5g30 Orange Granules$72.50
Prescription Generics

false

International Brands

Colestid

Synonyms

Colestipolum Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane

Manufacturers

Pharmacia And Upjohn Company Llc

CAS number

26658-42-4

UNII

K50N755924

State

solid

Affected organisms

Humans and other mammals

Indication of Colestipol

For use, as adjunctive therapy to diet, for the reduction of elevated serum total and LDL-C in patients with primary hypercholesterolemia (elevated LDL-C) who do not respond adequately to diet.

Toxicity of Colestipol

Oral LD sub 50 /sub in rats is 1000 mg/kg. Symptoms of overdose may include eye irritation, constipation, abdominal cramps, nausea, vomiting, diarrhea, and hypersensitivity. However, as colestipol is not absorbed, the risk of systemic toxicity is low.

RX24 Drugs Disclaimer: before buying a Colestipol on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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