Save up -80% on Corticotropin
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Acthar
|$38,507.28||1 vial (5ml) 80 units/ml|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Corticotropin coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Corticotropin every time. What are you waiting for? Claim your prescription drug card now!
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Corticotropin volume of distribution
The volume of distribution is 30 +/- 15 L/kg.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Corticotropin
Corticotropin (ACTH or adrenocorticotropic hormone) is a polypeptide hormone produced and secreted by the pituitary gland. It is an important player in the hypothalamic-pituitary-adrenal axis.
Corticotropin mechanism of action
As a diagnostic aid (adrenocortical function), corticotropin combines with a specific receptor on the adrenal cell plasma membrane. In patients with normal adrenocortical function, it stimulates the initial reaction involved in the synthesis of adrenal steroids (including cortisol, cortisone, weak androgenic substances, and a limited quantity of aldosterone) from cholesterol by increasing the quantity of cholesterol within the mitochondria. Corticotropin does not significantly increase serum cortisol concentrations in patients with primary adrenocortical insufficiency (Addison’s disease). The mechanism of action of corticotropin in the treatment of infantile myoclonic seizures is unknown.
Dosage forms of Corticotropin
|Gel||intramuscular; subcutaneous||40 unit|
|Powder for solution||intramuscular; intravenous; subcutaneous||40 unit|
Acthar Gel Hp Inj 40unit/ml
Armour Pharmaceutical Co.
Humans and other mammals
Indication of Corticotropin
For use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.
Toxicity of Corticotropin
Long-term use may cause possible hypersensitization; posterior subcapsulary cataracts and glaucoma; extreme irritability; discoloration of skin; shortness of breath; swelling of feet or lower legs; high blood pressure; hyperglycemia; hypothalamic-pituitary suppression; metabolic abnormalities, such as hypernatraemia, hypokalemia, hypocalcemia, and hypophosphatemia; blood toxins; rounding of face; excessive hair growth; dry skin or scalp; adrenocortical cell hyperplasia; adrenal hemorrhage; and swelling of the adrenal glands.
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