Save up -80% on Cosyntropin

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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Cosyntropin

Synacthen Depot 1 mg/vial



* price without discount in nearest pharmacy. Price may vary.

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Cosyntropin volume of distribution

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What is Cosyntropin

A synthetic peptide that is identical to the 24-amino acid segment at the N-terminal of adrenocorticotropic hormone. ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production of corticosteroids in the adrenal cortex.

Cosyntropin mechanism of action

Cosyntropin combines with a specific receptor in the adrenal cell plasma membrane and, in patients with normal adrenocortical function, stimulates the initial reaction involved in the synthesis of adrenal steroids (including cortisol, cortisone, weak androgenic substances, and a limited quantity of aldosterone) from cholesterol by increasing the quantity of the substrate within the mitochondria. Cosyntropin does not significantly increase plasma cortisol concentration in patients with primary or secondary adrenocortical insufficiency.

Dosage forms of Cosyntropin

Injection, powder, for solutionintramuscular; intravenous; parenteral.25 mg/mL
Injection, powder, lyophilized, for solutionintramuscular; intravenous.25 mg/mL
Powder for solutionintramuscular; intravenous0.25 mg
Prescription Generics


International Brands



Adrenocorticotropic hormone 1-24 alpha(1-24)-Corticotrophin


General Injectables – Vaccines, Inc

CAS number






Affected organisms

Humans and other mammals

Indication of Cosyntropin

For use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.

Toxicity of Cosyntropin

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