Save up -80% on Crofelemer
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Mytesi
|$303||30 tablets/125 mg|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Crofelemer coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Crofelemer every time. What are you waiting for? Claim your prescription drug card now!
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Crofelemer volume of distribution
Since crofelemer is not significantly absorbed, volume of distribution was not quantified.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Crofelemer
Crofelemer, previously known as the investigational drug SP-303, is a novel proanthocyanidin purified from the bark latex of the Amazonian Croton tree iCroton lechleri/i. It is marketed under the brand name Fulyzaq and indicated for the symptomatic treatment of non-infectious diarrhea in adult patients with HIV/AIDS who are taking antiretroviral therapy.
Crofelemer mechanism of action
Crofelemer is an inhibitor of the cystic fibrosis transmembrane regulator chloride channel (CFTR), as evidenced by its activity on cell cultures, single cell patch clamps, single CFTR channels, and elaboration of mouse intestinal fluid secretion. Crofelemer also inhibits calcium activated chloride channels (CaCC), which in combination with CFTR, are expressed on the luminal side of intestinal cells. Crofelemer inhibition of both of these channels prevents water loss from diarrhea by inhibiting chloride secretion.
Dosage forms of Crofelemer
|Tablet, coated||oral||125 mg/1|
Salix Pharmaceuticals, Inc.
Humans and other mammals
Indication of Crofelemer
For the symptomatic treatment of non-infectious diarrhea in adult patients with HIV/AIDS who are taking antiretroviral therapy.
Toxicity of Crofelemer
The most common adverse effects are cough, flatulence, upper respiratory tract infection, bronchitis, and increased bilirubin.
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