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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Cyanocobalamin

Cyanocobalamin 1000 mcg/ml Solution

$1.03

ml

* price without discount in nearest pharmacy. Price may vary.

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Cyanocobalamin volume of distribution

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What is Cyanocobalamin

Cyanocobalamin (commonly known as Vitamin B12) is the most chemically complex of all the vitamins. Cyanocobalamin’s structure is based on a corrin ring, which, although similar to the porphyrin ring found in heme, chlorophyll, and cytochrome, has two of the pyrrole rings directly bonded. The central metal ion is Co (cobalt). Cyanocobalamin cannot be made by plants or by animals, as the only type of organisms that have the enzymes required for the synthesis of cyanocobalamin are bacteria and archaea. Higher plants do not concentrate cyanocobalamin from the soil and so are a poor source of the substance as compared with animal tissues. Cyanocobalamin is naturally found in foods including meat (especially liver and shellfish), eggs, and milk products.[HMDB]

Cyanocobalamin mechanism of action

Vitamin B12 is used in the body in two forms: Methylcobalamin and 5-deoxyadenosyl cobalamin. The enzyme methionine synthase needs methylcobalamin as a cofactor. This enzyme is involved in the conversion of the amino acid homocysteine into methionine. Methionine in turn is required for DNA methylation. 5-Deoxyadenosyl cobalamin is a cofactor needed by the enzyme that converts L-methylmalonyl-CoA to succinyl-CoA. This conversion is an important step in the extraction of energy from proteins and fats. Furthermore, succinyl CoA is necessary for the production of hemoglobin, the substances that carries oxygen in red blood cells.

Dosage forms of Cyanocobalamin

FormRouteStrength
Liquid; capsuleoral
Elixiroral
Tabletoral1000 mcg
Prescription Generics

false

International Brands

Active Fe

Synonyms

Cyanocob(III)alamin Vitamin B12

Manufacturers

Gm Pharmaceuticals, Inc.

CAS number

68-19-9

UNII

P6YC3EG204

State

solid

Affected organisms

Humans and other mammals

Indication of Cyanocobalamin

For treatment of pernicious anemia (due to lack of or inhibition of intrinsic factor) and for prevention and treatment of vitamin B 12 deficiency.

Toxicity of Cyanocobalamin

Anaphylactic reaction (skin rash, itching, wheezing)-after parenteral administration. ORL-MUS LD sub50 /sub 8000 mg/kg

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