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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Cyclobenzaprine

Cyclobenzaprine 5 mg tablet

$1.64

tablet

* price without discount in nearest pharmacy. Price may vary.

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Cyclobenzaprine volume of distribution

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What is Cyclobenzaprine

Cyclobenzaprine is a skeletal muscle relaxant and a central nervous system (CNS) depressant. Cyclobenzaprine acts on the locus coeruleus where it results in increased norepinephrine release, potentially through the gamma fibers which innervate and inhibit the alpha motor neurons in the ventral horn of the spinal cord. It is structurally similar to Amitriptyline, differing by only one double bond.

Cyclobenzaprine mechanism of action

Like other tricyclic antidepressants, cyclobenzaprine exhibits anticholinergic activity, potentiation of norepinephrine, and antagonism of reserpine. Cyclobenzaprine does not directly act on the neuromuscular junction or the muscle but relieves muscle spasms through a central action, possibly at the brain stem level. Cyclobenzaprine binds to the serotonin receptor and is considered a 5-HT2 receptor antagonist that reduces muscle tone by decreasing the activity of descending serotonergic neurons.

Dosage forms of Cyclobenzaprine

FormRouteStrength
Capsule, extended releaseoral15 mg/1
Capsule, extended releaseoral30 mg/1
Tabletoral10 mg
Prescription Generics

false

International Brands

Alti-cyclobenzaprine – Tab 10mg

Synonyms

(3-Dibenzo(a,d)cyclohepten-5-ylidene-propyl)-dimethyl-amine Ciclobenzaprina

Manufacturers

Altimed Pharma Inc.

CAS number

303-53-7

UNII

69O5WQQ5TI

State

solid

Affected organisms

Humans and other mammals

Indication of Cyclobenzaprine

For use as an adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions.

Toxicity of Cyclobenzaprine

Oral mouse and rat LD sub 50 /sub are 338 mg/kg and 425 mg/kg respectively. Signs of overdose include agitation, coma, confusion, congestive heart failure, convulsions, dilated pupils, disturbed concentration, drowsiness, hallucinations, high or low temperature, increased heartbeats, irregular heart rhythms, muscle stiffness, overactive reflexes, severe low blood pressure, stupor, and vomiting.

RX24 Drugs Disclaimer: before buying a Cyclobenzaprine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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