Save up -80% on Cycloserine
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Price of Cycloserine
Seromycin 250 mg pulvule
* price without discount in nearest pharmacy. Price may vary.
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Cycloserine volume of distribution
What is Cycloserine
Antibiotic substance produced by Streptomyces garyphalus. (PubChem)
Cycloserine mechanism of action
Cycloserine is an analog of the amino acid D-alanine. It interferes with an early step in bacterial cell wall synthesis in the cytoplasm by competitive inhibition of two enzymes, L-alanine racemase, which forms D-alanine from L-alanine, and D-alanylalanine synthetase, which incorporates D-alanine into the pentapeptide necessary for peptidoglycan formation and bacterial cell wall synthesis.
Dosage forms of Cycloserine
Purdue GMP Center LLC dba The Chao Center
Enteric bacteria and other eubacteria
Indication of Cycloserine
Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB).
Toxicity of Cycloserine
Oral LD sub 50 /sub in mouse is 5290 mg/kg, and in rat is over 5000 mg/kg. Symptoms of a cycloserine overdose include drowsiness, confusion, headache, dizziness, irritability, numbness and tingling, difficulty speaking, paralysis, abnormal behavior, seizures, and unconsciousness.
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