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2018 Price of Cysteamine
Cystagon 150 mg capsule
capsule
* price without discount in nearest pharmacy. Price may vary.
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Cysteamine volume of distribution
Cystagon has a volume of distribution of 156 L.
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What is Cysteamine
Cysteamine is a radiation-protective agent that oxidizes in air to form cystamine. It can be given intravenously or orally to treat radiation sickness. The bitartrate and hydrochloride salt forms are indicated for the treatment of neuropathic cystinosis in patients 6 years old and older.. Cysteamine is marketed under several brand names such as Cystaran, Procysbi, and Cystagon.
Cysteamine mechanism of action
The free thiol cysteamine depletes cystinotic leukocytes and other cells of cystine, whose accumulation is considered the cause of organ damage in cystinosis. Cysteamine cleaves the disulfide bond with cystine to produce molecules that can escape the metabolic defect in cystinosis and cystinuria.
Dosage forms of Cysteamine
| Form | Route | Strength |
|---|---|---|
| Capsule | oral | 150 mg/1 |
| Capsule | oral | 50 mg/1 |
| Hard capsule | Oral use | 150 mg |
Prescription Generics
false
International Brands
Cystagon
Synonyms
2-Amino-1-ethanethiol 2-AMINO-ethanethiol
Manufacturers
Mylan Pharmaceuticals Inc.
CAS number
60-23-1
UNII
5UX2SD1KE2
State
solid
Affected organisms
Humans and other mammals
Indication of Cysteamine
Given intravenously or orally to treat radiation sickness. The bitartrate salts (Cystagon and Procysbi) have been used for the oral treatment of nephropathic cystinosis and cystinurea. The hydrochloride salt (Cystaran) is indicated for the treatment of corneal cystine crystal accumulation in cystinosis patients.
Toxicity of Cysteamine
Symptoms of overdose may include convulsions (seizures), increased thirst and unusual tiredness or weakness.
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