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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Cytarabine

Cytarabine 1 gm vial

$24.0

vial

* price without discount in nearest pharmacy. Price may vary.

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Cytarabine volume of distribution

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What is Cytarabine

A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)

Cytarabine mechanism of action

Cytarabine acts through direct DNA damage and incorporation into DNA. Cytarabine is cytotoxic to a wide variety of proliferating mammalian cells in culture. It exhibits cell phase specificity, primarily killing cells undergoing DNA synthesis (S-phase) and under certain conditions blocking the progression of cells from the G1 phase to the S-phase. Although the mechanism of action is not completely understood, it appears that cytarabine acts through the inhibition of DNA polymerase. A limited, but significant, incorporation of cytarabine into both DNA and RNA has also been reported.

Dosage forms of Cytarabine

FormRouteStrength
Injectionintrathecal; intravenous; subcutaneous100 mg/5mL
Injectionintrathecal; intravenous; subcutaneous2 g/20mL
Injectionintravenous; subcutaneous20 mg/mL
Prescription Generics

false

International Brands

Aj-cytarabine

Synonyms

1-beta-D-Arabinofuranosylcytosine 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone

Manufacturers

Agila Jamp Canada Inc

CAS number

147-94-4

UNII

04079A1RDZ

State

solid

Affected organisms

Humans and other mammals

Indication of Cytarabine

For the treatment of acute non-lymphocytic leukemia, acute lymphocytic leukemia and blast phase of chronic myelocytic leukemia.

Toxicity of Cytarabine

Cytarabine syndrome may develop – it is characterized by fever, myalgia, bone pain, occasionally chest pain, maculopapular rash, conjunctivitis, and malaise.

RX24 Drugs Disclaimer: before buying a Cytarabine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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