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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Dacarbazine

Dacarbazine 100 mg vial

$11.34

vial

* price without discount in nearest pharmacy. Price may vary.

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Dacarbazine volume of distribution

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What is Dacarbazine

An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.

Dacarbazine mechanism of action

The mechanism of action is not known, but appears to exert cytotoxic effects via its action as an alkylating agent. Other theories include DNA synthesis inhibition by its action as a purine analog, and interaction with SH groups. Dacarbazine is not cell cycle-phase specific.

Dosage forms of Dacarbazine

FormRouteStrength
Injection, powder, for solutionintravenous10 mg/mL
Injection, powder, for solutionintravenous200 mg/20mL
Powder for solutionintravenous600 mg
Prescription Generics

true

International Brands

Dacarbazine

Synonyms

4-(3,3-Dimethyl-1-triazeno)imidazole-5-carboxamide 4-(5)-(3,3-Dimethyl-1-triazeno)imidazole-5(4)-carboxamide

Manufacturers

APP Pharmaceuticals, LLC

CAS number

4342-03-4

UNII

7GR28W0FJI

State

solid

Affected organisms

Humans and other mammals

Indication of Dacarbazine

For the treatment of metastatic malignant melanoma. In addition, dacarbazine is also indicated for Hodgkin’s disease as a secondary-line therapy when used in combination with other antineoplastic agents.

Toxicity of Dacarbazine

LDsub50/sub=350mg/kg (orally in mice)

RX24 Drugs Disclaimer: before buying a Dacarbazine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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