Save up -80% on Dalfopristin

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Synercid

$410.031 vial/500 mg
Price with discount in nearest pharmacy. Price may vary.

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Dalfopristin volume of distribution

The clearances of unchanged quinupristin and dalfopristin are similar (0.72 L/h/kg), and the steady-state volume of distribution for quinupristin is 0.45 L/kg and for dalfopristin is 0.24 L/kg. The elimination half-life of quinupristin and dalfopristin is approximately 0.85 and 0.70 hours, respectively.

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2018 Statistics

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Discount Cards 16,000+

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Clients Benefit 29%

savings

Total savings $4,735,080

What is Dalfopristin

Dalfopristin is a combination of two antibiotics (Dalfopristin and quinupristin used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium. It is not effective against Enterococcus faecalis infections. Dalfopristin inhibits the early phase of protein synthesis in the bacterial ribosome and quinupristin inhibits the late phase of protein synthesis.

Dalfopristin mechanism of action

The site of action of dalfopristin is the bacterial ribosome. Dalfopristin has been shown to inhibit the early phase of protein synthesis.

Dosage forms of Dalfopristin

FormRouteStrength
Injection, powder, lyophilized, for solutionintravenous
Powder for solutionintravenous

Prescription Generics

false

International Brands

Synercid

Synonyms

Dalfopristina Dalfopristine

Manufacturers

Monarch Pharmaceuticals Ireland Limited

CAS number

112362-50-2

UNII

R9M4FJE48E

State

solid

Affected organisms

Enteric bacteria and other eubacteria

Indication of Dalfopristin

For the treatment of bacterial infections (usually in combination with quinupristin).

Toxicity of Dalfopristin

Synercid, dalfopristin, and quinupristin were all negative in the other four genetic toxicity assays. No impairment of fertility or perinatal/postnatal development was observed in rats at doses up to 12 to 18 mg/kg (approximately 0.3 to 0.4 times the human dose based on body-surface area).

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