Save up -80% on Deferiprone
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Ferriprox
|$17,388.32||270 tablets/500 mg|
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Deferiprone coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Deferiprone every time. What are you waiting for? Claim your prescription drug card now!
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Deferiprone volume of distribution
In healthy patients, the volume of distribution is 1L/kg, and in thalassemia patients, the volume of distribution is 1.6L/kg.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Deferiprone
Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired. FDA approved on October 14, 2011.
Deferiprone mechanism of action
Deferiprone is an iron chelator that binds to ferric ions (iron III) and forms a 3:1 (deferiprone:iron) stable complex and is then eliminated in the urine. Deferiprone is more selective for iron in which other metals such as zinc, copper, and aluminum have a lower affinity for deferiprone.
Dosage forms of Deferiprone
|Film-coated tablet||Oral use||1000 mg|
|Film-coated tablet||Oral use||500 mg|
|Oral solution||Oral use||100 mg/ml|
Humans and other mammals
Indication of Deferiprone
Deferiprone is indicated in thalassemia syndromes when first line chelation agents are not adequate to treat transfusional iron overload.
Toxicity of Deferiprone
Agranulocytosis and neutropenia may occur, which can lead to fatal infections. Hepatoxicity is also possible. Most common side effects that lead to discontinuation of therapy were the gastrointestinal adverse effects (diarrhea, ulcer, nausea, gastrointestinal disturbances)
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