Save up -80% on Denileukin diftitox

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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Denileukin diftitox

Ontak 150 mcg/ml vial



* price without discount in nearest pharmacy. Price may vary.

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Denileukin diftitox volume of distribution

* 0.06 to 0.09 L/kg

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What is Denileukin diftitox

A recombinant DNA-derived cytotoxic protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met 1-Thr 387)-His followed by the sequences for interleukin-2 (IL-2; Ala 1-Thr 133). It is produced in an E. coli expression system.

Denileukin diftitox mechanism of action

Denileukin diftitox binds to the high-affinity IL-2 receptor complex. The IL-2 receptor (Tac) subunit is expressed on activated but not resting lymphocytes. The diphtheria toxin associated with Ontak then selectively kills the IL-2 bearing cells.

Dosage forms of Denileukin diftitox

Form Route Strength
Injection, solution intravenous 150 ug/mL
Prescription Generics


International Brands



Diphtheria toxin precursor DT


Eisai Inc.

CAS number






Affected organisms

Humans and other mammals

Indication of Denileukin diftitox

For treatment of cutaneous T-cell lymphoma

Toxicity of Denileukin diftitox

RX24 Drugs Disclaimer: before buying a Denileukin diftitox on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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