Save up -80% on Desflurane
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Desflurane
Suprane inhalation liquid
|price without discount in nearest pharmacy. Price may vary.|
We offer free Desflurane coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Desflurane every time. What are you waiting for? Claim your prescription drug card now!
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Desflurane volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Desflurane
Desflurane is a highly fluorinated methyl ethyl ether used for maintenance of general anaesthesia. Volatile agents such as desflurane may activate GABA channels and hyperpolarize cell membranes. In addition, they may inhibit certain calcium channels and therefore prevent release of neurotransmitters and inhibit glutamate channels. Volatile anesthetics easily partition into cellular membranes and could expand the volume of the cell membrane and subsequently distort channels necessary for sodium ion flux and the development of action potentials necessary for synaptic transmission. Desflurane preconditions human myocardium against ischemia through activation of mitochondrial K(ATP) channels, adenosine A1 receptor, and alpha and beta adrenoceptors.
Desflurane mechanism of action
Desflurane induces a reduction in junctional conductance by decreasing gap junction channel opening times and increasing gap junction channel closing times. Desflurane also activates calcium dependent ATPase in the sarcoplasmic reticulum by increasing the fluidity of the lipid membrane. It also appears to bind the D subunit of ATP synthase and NADH dehydogenase. Desflurane also binds to and agonizes the GABA receptor, the large conductance Ca sup2+ /sup activated potassium channel, the glycine receptors, and antagonizes the glutamate receptors.
Dosage forms of Desflurane
|Liquid||respiratory (inhalation)||240 mL/240mL|
(+-)-2-Difluoromethyl 1,2,2,2-tetrafluoroethyl ether 1,1,1,2-Tetrafluoro-2-(difluoromethoxy)ethane
Humans and other mammals
Indication of Desflurane
For use as an inhalation agent for induction and/or maintenance of anesthesia for inpatient and outpatient surgery in adults.
Toxicity of Desflurane
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