Save up -80% on Desloratadine

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Clarinex

$78.6510 tablets/5mg
price without discount in nearest pharmacy. Price may vary.

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We offer free Clarinex coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Desloratadine every time. What are you waiting for? Claim your prescription drug card now!

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Desloratadine volume of distribution

The apparent volume of distribution is limited for levocetirizine (0.4 L/kg) and mizolastine (1-1.2 L/kg), larger for fexofenadine (5.4-5.8 L/kg) and particularly large for desloratadine (approximately 49 l/kg).

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2018 Statistics

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Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Desloratadine

Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.

Desloratadine mechanism of action

Like other H1-blockers, Desloratadine competes with free histamine for binding at H sub 1 /sub -receptors in the GI tract, uterus, large blood vessels, and bronchial smooth muscle. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms (eg. nasal congestion, watery eyes) brought on by histamine.

Dosage forms of Desloratadine

FormRouteStrength
Tabletoral5 mg
Tablet (extended-release)oral
Tablet (immediate and extended release)oral

Prescription Generics

false

International Brands

Aerius

Synonyms

8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridine 8-chloro-6,11-dihydro-11-(4-Piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine

Manufacturers

Bayer Inc Consumer Care

CAS number

100643-71-8

UNII

FVF865388R

State

solid

Affected organisms

Humans and other mammals

Indication of Desloratadine

For the relief of symptoms of seasonal allergic rhinitis, perennial (non-seasonal) allergic rhinitis. Desloratidine is also used for the sympomatic treatment of pruritus and urticaria (hives) associated with chronic idiopathic urticaria.

Toxicity of Desloratadine

Significant cardiac toxicity has been associated with some older antihistamines (eg, terfenadine and astemizole) when their plasma concentrations are increased. There is thus a need for a thorough assessment of the cardiac safety of newer antihistamine compounds.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Desloratadine on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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