Save up -80% on Desonide
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2018 Price of Desonide
Desowen 0.05% cream
* price without discount in nearest pharmacy. Price may vary.
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Desonide volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Desonide
A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
Desonide mechanism of action
Like other topical corticosteroids, desonide has anti-inflammatory, antipruritic and vasoconstrictive properties. The drug binds to cytosolic glucocorticoid receptors. This complex migrates to the nucleus and binds to genetic elements on the DNA. This activates and represses various genes. However corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2.
Dosage forms of Desonide
Desocort Cream 0.05%
Galderma Canada Inc
Humans and other mammals
Indication of Desonide
For the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatose.
Toxicity of Desonide
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