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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Desoximetasone

Desoximetasone 0.05% cream

$1.29

g

* price without discount in nearest pharmacy. Price may vary.

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Desoximetasone volume of distribution

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What is Desoximetasone

A topical anti-inflammatory glucocorticoid used in dermatoses, skin allergies, psoriasis, etc.

Desoximetasone mechanism of action

The precise mechanism of the antiinflammatory activity of topical steroids in the treatment of steroid-responsive dermatoses, in general, is uncertain. However, corticosteroids are thought to act by the induction of phospholipase A sub2 /sub inhibitory proteins, collectively called lipocortins. This is achieved first by the drug binding to the glucocorticoid receptors which then translocates into the nucleus and binds to DNA causing various activations and repressions of genes. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A sub2 /sub.

Dosage forms of Desoximetasone

FormRouteStrength
Creamtopical0.25 %
Creamtopical.5 mg/g
Creamtopical2.5 mg/g
Prescription Generics

false

International Brands

Desoxi Cream 0.05%

Synonyms

(11beta,16alpha)-9-Fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione 9alpha-Fluoro-16alpha-methyl-delta(1)-corticosterone

Manufacturers

Taropharma, A Division Of Taro Pharmaceuticals Inc.

CAS number

382-67-2

UNII

4E07GXB7AU

State

solid

Affected organisms

Humans and other mammals

Indication of Desoximetasone

For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Toxicity of Desoximetasone

Topically applied desoximetasone can be absorbed in sufficient amounts to produce systemic effects. Symptoms of overdose include thinning of skin and suppression of adrenal cortex (decreased ability to respond to stress).

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