Save up -80% on Dexamethasone
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Decadron
|$10.01||30 tablets/4 mg|
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Dexamethasone coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Dexamethasone every time. What are you waiting for? Claim your prescription drug card now!
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Dexamethasone volume of distribution
Standard dose dexamethasone administration appears to follow first order kinetics with peak values of 1.5 mcg/ml occurring 30 minutes, volume of distribution of 648 ml/kg, half-life of 4 hrs, and clearance of 111.2 ml/kg/hr.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Dexamethasone
Dexamethasone is a steroid that prevents the release of substances in the body that cause inflammation. Dexamethasone is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders.
Dexamethasone mechanism of action
Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. This complex binds to DNA elements (glucocorticoid response elements) which results in a modification of transcription and, hence, protein synthesis in order to achieve inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, suppression of humoral immune responses, and reduction in edema or scar tissue. The antiinflammatory actions of dexamethasone are thought to involve phospholipase A sub2 /sub inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.
Dosage forms of Dexamethasone
|Implant||nil; refer (see dosage form)||.7 mg|
999 Itch Relief
China Resources Sanjiu Medical Pharmaceutical Co Ltd
Humans and other mammals
Indication of Dexamethasone
BInjection: /B for the treatment of endocrine disorders, rheumatic D=disorders, collagen diseases, dermatologic diseases, allergic statesc, ophthalmic diseases, gastrointestinal diseases, respiratory diseases, hematologic disorders, neoplastic diseases, edematous states, cerebral edema. br BOphthalmic ointment and solution: /B for the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe. br BOphthalmic solution only: /B for the treatment of steroid responsive inflammatory conditions of the external auditory meatus br BTopic cream: /B for relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses br BOral aerosol: /B for the treatment of bronchial asthma and related corticosteroid responsive bronchospastic states intractable to adequate trial of conventional therapy br BIntranasal aerosol: /B for the treatment of allergic ot inflammatory nasal conditions, and nasal polyps
Toxicity of Dexamethasone
Oral, rat LD sub50 /sub: 3 gm/kg. Signs of overdose include retinal toxicity, glaucoma, subcapsular cataract, gastrointestinal bleeding, pancreatitis, aseptic bone necrosis, osteoporosis, myopathies, obesity, edemas, hypertension, proteinuria, diabetes, sleep disturbances, psychiatric syndromes, delayed wound healing, atrophy and fragility of the skin, ecchymosis, and pseudotumor cerebri.
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