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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Dextroamphetamine

Dexedrine 15 mg Sustained-Release Capsule

$1.08

capsule

* price without discount in nearest pharmacy. Price may vary.

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Dextroamphetamine volume of distribution

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What is Dextroamphetamine

Dextroamphetamine is the dextrorotary stereoisomer of the amphetamine molecule, which can take two different forms. It is a slightly polar, weak base and is lipophilic.

Dextroamphetamine mechanism of action

The exact mechanism of action is not known. Dextroamphetamine stimulates the release of norepinephrine from central adrenergic receptors. At higher dosages, it causes release of dopamine from the mesocorticolimbic system and the nigrostriatal dopamine systems by reversal of the monoamine transporters. Dextroamphetamine may also act as a direct agonist on central 5-HT receptors and may inhibit monoamine oxidase (MAO). In the periphery, amphetamines are believed to cause the release of noradrenaline by acting on the adrenergic nerve terminals and alpha- and beta-receptors. Modulation of serotonergic pathways may contribute to the calming affect.

Dosage forms of Dextroamphetamine

FormRouteStrength
Capsule (extended release)oral
Capsule (sustained-release)oral10 mg
Capsule (sustained-release)oral15 mg
Prescription Generics

false

International Brands

Act Amphetamine XR

Synonyms

(+)-(S)-amphetamine (+)-alpha-Methylphenethylamine

Manufacturers

Actavis Pharma Company

CAS number

51-64-9

UNII

TZ47U051FI

State

solid

Affected organisms

Humans and other mammals

Indication of Dextroamphetamine

Used to treat attention deficit hyperactivity disorder (ADHD).

Toxicity of Dextroamphetamine

In rats, the oral LD50 of dextroamphetamine sulfate is 96.8 mg/kg. Manifestations of acute overdosage with amphetamines include restlessness, tremor, hyperreflexia, rhabdomyolysis, rapid respiration, hyperpyrexia, confusion, assaultiveness, hallucinations, panic states. Fatigue and depression usually follow the central stimulation. Cardiovascular effects include arrhythmias, hypertension or hypotension, and circulatory collapse. Gastrointestinal symptoms include nausea, vomiting, diarrhea, and abdominal cramps. Fatal poisoning is usually preceded by convulsions and coma.

RX24 Drugs Disclaimer: before buying a Dextroamphetamine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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