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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Zenzedi

$42.0860 tablets/10 mg
price without discount in nearest pharmacy. Price may vary.

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We offer free Dextroamphetamine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Dextroamphetamine every time. What are you waiting for? Claim your prescription drug card now!

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Dextroamphetamine volume of distribution

A one-compartment plasma model linked to a single compartment for hair successfully described the pharmacokinetics of dextroamphetamine in healthy adults. The volume of distribution and clearance of dextroamphetamine increased with weight, and the volume of distribution of the hair compartment increased with greater melanin concentrations.

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2018 Statistics

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Discount Cards 16,000+

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Clients Benefit 29%

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Total savings $4,735,080

What is Dextroamphetamine

Dextroamphetamine is the dextrorotary stereoisomer of the amphetamine molecule, which can take two different forms. It is a slightly polar, weak base and is lipophilic.

Dextroamphetamine mechanism of action

The exact mechanism of action is not known. Dextroamphetamine stimulates the release of norepinephrine from central adrenergic receptors. At higher dosages, it causes release of dopamine from the mesocorticolimbic system and the nigrostriatal dopamine systems by reversal of the monoamine transporters. Dextroamphetamine may also act as a direct agonist on central 5-HT receptors and may inhibit monoamine oxidase (MAO). In the periphery, amphetamines are believed to cause the release of noradrenaline by acting on the adrenergic nerve terminals and alpha- and beta-receptors. Modulation of serotonergic pathways may contribute to the calming affect.

Dosage forms of Dextroamphetamine

FormRouteStrength
Capsule (extended release)oral
Capsule (sustained-release)oral10 mg
Capsule (sustained-release)oral15 mg

Prescription Generics

false

International Brands

Act Amphetamine XR

Synonyms

(+)-(S)-amphetamine (+)-alpha-Methylphenethylamine

Manufacturers

Actavis Pharma Company

CAS number

51-64-9

UNII

TZ47U051FI

State

solid

Affected organisms

Humans and other mammals

Indication of Dextroamphetamine

Used to treat attention deficit hyperactivity disorder (ADHD).

Toxicity of Dextroamphetamine

In rats, the oral LD50 of dextroamphetamine sulfate is 96.8 mg/kg. Manifestations of acute overdosage with amphetamines include restlessness, tremor, hyperreflexia, rhabdomyolysis, rapid respiration, hyperpyrexia, confusion, assaultiveness, hallucinations, panic states. Fatigue and depression usually follow the central stimulation. Cardiovascular effects include arrhythmias, hypertension or hypotension, and circulatory collapse. Gastrointestinal symptoms include nausea, vomiting, diarrhea, and abdominal cramps. Fatal poisoning is usually preceded by convulsions and coma.

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What is Zenzedi?

Zenzedi is an immediate-release stimulant medication — a tablet taken orally that is primarily used to treat narcolepsy and ADHD in children and adolescents ages 3-16. According to the FDA, Zenzedi is a federally controlled substance (CII) because it can be abused or lead to dependence. It is an amphetamine.

Zenzedi may improve focus and decrease impulsivity and hyperactive behavior, two hallmark symptoms for some patients with ADHD.

The American Academy of Pediatrics recommends treatment with behavioral therapy before medication for children under the age of 6. For children ages 6 to 11, the AAP says most effective treatments for ADHD are parental behavior therapy and/or ADHD stimulants. Likewise, the National Institute of Mental Health finds the most successful treatment plans use a combination of ADHD medication, like Zenzedi, and behavior therapies.