Save up -80% on Dextromethorphan

Note: this is a drug discount program, not an insurance plan.

RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Dextromethorphan

Dextromethorphan hbr cryst

$2.06

g

* price without discount in nearest pharmacy. Price may vary.

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Dextromethorphan volume of distribution

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What is Dextromethorphan

The d-isomer of the codeine analog of levorphanol. Dextromethorphan shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (receptors, N-methyl-D-aspartate) and acts as a non-competitive channel blocker. It is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.

Dextromethorphan mechanism of action

Dextromethorphan is an opioid-like drug that binds to and acts as antagonist to the NMDA glutamatergic receptor, it is an agonist to the opioid sigma 1 and sigma 2 receptors, it is also an alpha3/beta4 nicotinic receptor antagonist and targets the serotonin reuptake pump. Dextromethorphan is rapidly absorbed from the gastrointestinal tract, where it enters the bloodstream and crosses the blood-brain barrier. The first-pass through the hepatic portal vein results in some of the drug being metabolized into an active metabolite of dextromethorphan, dextrorphan, the 3-hydroxy derivative of dextromethorphan.

Dosage forms of Dextromethorphan

FormRouteStrength
Capsuleoral15 mg/1
Solutionoral30 mg/10mL
Kit
Prescription Generics

true

International Brands

12 Hour Cough Relief

Synonyms

(+)-dextromethorphan D-methorphan

Manufacturers

Western Family Foods Inc

CAS number

125-71-3

UNII

7355X3ROTS

State

solid

Affected organisms

Humans and other mammals

Indication of Dextromethorphan

For treatment and relief of dry cough.

Toxicity of Dextromethorphan

RX24 Drugs Disclaimer: before buying a Dextromethorphan on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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