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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Diatrizoate

Cysto-conray 17.2% vial

$0.11

ml

* price without discount in nearest pharmacy. Price may vary.

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Diatrizoate volume of distribution

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What is Diatrizoate

A commonly used x-ray contrast medium. As diatrizoate meglumine and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography.

Diatrizoate mechanism of action

Diatrizoate is an iodine-containing X-ray contrast agent. Iodated contrast agents were among the first contrast agents developed. Iodine is known to be particular electron-dense and to effectively scatter or stop X-rays. A good contrast agent requires a high density of electron-dense atoms. Therefore, the more iodine, the more “dense” the x-ray effect. Iodine based contrast media are water soluble and harmless to the body. These contrast agents are sold as clear colorless water solutions, the concentration is usually expressed as mg I/ml. Modern iodinated contrast agents can be used almost anywhere in the body. Most often they are used intravenously, but for various purposes they can also be used intraarterially, intrathecally (the spine) and intraabdominally – just about any body cavity or potential space.

Dosage forms of Diatrizoate

FormRouteStrength
Injection, solutionintravenous300 mg/mL
Injection, solutionintravesical180 mg/mL
Liquidoral; rectal
Prescription Generics

false

International Brands

Cystografin

Synonyms

2,4,6-Triiodo-3,5-diacetamidobenzoic acid 3,5-Bis(acetylamino)-2,4,6-triiodobenzoic acid

Manufacturers

BRACCO DIAGNOSTICS INC

CAS number

117-96-4

UNII

5UVC90J1LK

State

solid

Affected organisms

Humans and other mammals

Indication of Diatrizoate

Used, alone or in combination, for a wide variety of diagnostic imaging methods, including angiography, urography, cholangiography, computed tomography, hysterosalpingography, and retrograde pyelography. It can be used for imaging the gastrointestinal tract in patients allergic to barium.

Toxicity of Diatrizoate

High osmolal radiocontrast agents like diatrizoate are cytotoxic to renal cells. The toxic effects include apoptosis, cellular energy failure, disruption of calcium homeostasis, and disturbance of tubular cell polarity, and are thought to be linked to oxidative stress.

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