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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Voltaren Gel

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Diclofenac volume of distribution

The apparent volume of distribution (V/F) of diclofenac sodium is 1.4 L/kg. Diclofenac is more than 99% bound to human serum proteins, primarily to albumin.

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What is Diclofenac

A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.

Diclofenac mechanism of action

The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation.

Dosage forms of Diclofenac

Diclofenac Sodium25mg100 Tablet EC$39.00
Diclofenac sodium1.50%60mL Solution$136.00
Diclofenac Sodium0.10%10mL Ophthalmic Solution$60.00
Diclofenac Sr100mg100 Tablet SR$75.00
Diclofenac Diethylamine Transdermal Patch200mg90 Patch$267.00
Diclofenac Potassium50mg84 Tablet$50.00
Voltaren SR100mg90 Tablet SA$84.36
Voltaren Suppositories50mg30 Suppository$69.00
Voltaren Ophthalmic Solution0.10%5mL Ophthalmic Solution$40.00
Voltaren Rapid K50mg100 Tablet$132.00
Voltaren Gel1.16%100g Gel$41.00
Voltaren Gel Extra Strength2.32%90g Gel$56.00
Arthrotec50/200mcg120 Tablet$102.00
Arthrotec75/200mcg180 Tablet$187.00
Flector Patch1.30%30 Patch$395.00
Pennsaid1.50%120mL Solution$136.00
Solaraze Gel3%100g Gel$195.00
Cambia50mg9sachets Powder for Oral Solution$145.00

Prescription Generics


International Brands

Act Diclo-miso


(2-(2,6-dichloroanilino)phenyl)acetic acid 2-((2,6-dichlorophenyl)amino)benzeneacetic acid


Actavis Pharma Company

CAS number






Affected organisms

Humans and other mammals

Indication of Diclofenac

For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.

Toxicity of Diclofenac

Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD sub50 /sub=390mg/kg (orally in mice)

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Diclofenac on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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What is Voltaren Gel?

Voltaren Gel contains diclofenac, a nonsteroidal anti-inflammatory drug (NSAID). Voltaren Gel works by reducing the substances in the body that cause pain and inflammation. Voltaren Gel is used to treat joint pain caused by osteoarthritis in the hands, wrists, elbows, knees, ankles, or feet. Voltaren Gel may not be effective in treating arthritis pain elsewhere in the body.

You should not use Voltaren Gel if you have ever had asthma or a severe allergic reaction caused by aspirin, diclofenac (Cataflam, Voltaren) or another nonsteroidal anti-inflammatory drug (NSAID).

Diclofenac may increase the risk of a fatal heart attack or stroke, especially if you use it for a long time or take high doses, or if you have heart disease. Do not use Voltaren Gel immediately before or after cardiac bypass surgery (coronary artery bypass or CABG). Diclofenac can also cause stomach or intestinal bleeding, which can be fatal. These conditions may occur without warning when you use Voltaren Gel, especially in older people.

What is Flector?

Flector Patch contains diclofenac, a non-steroidal anti-inflammatory drug (NSAID). Flector patch works by reducing substances in the body that cause pain and inflammation. Flector is used to treat pain caused by minor sprains, deformities, or bruising.