Save up -80% on Diclofenac
Note: this is a drug discount program, not an insurance plan.
Price of Diclofenac
Voltaren Sr 75 mg Sustained-Release Tablet
* price without discount in nearest pharmacy. Price may vary.
We offer free Diclofenac coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your coupon in most local pharmacies to get a discount on Diclofenac. Claim your prescription drug card now!
Diclofenac volume of distribution
* 1.3 L/kg
What is Diclofenac
A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. (PubChem)
Diclofenac mechanism of action
The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation.
Dosage forms of Diclofenac
|Tablet (enteric-coated)||oral||25 mg|
|Tablet (enteric-coated)||oral||50 mg|
Actavis Pharma Company
Humans and other mammals
Indication of Diclofenac
For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Toxicity of Diclofenac
Symptoms of overdose include loss of consciousness, increased intracranial pressure, and aspiration pneumonitis. LD sub50 /sub=390mg/kg (orally in mice)
Disclaimer: before buying a Diclofenac on prescription, consult your health care provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.