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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Dynapen

$31.240 capsules/500 mg
Price with discount in nearest pharmacy. Price may vary.

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Dicloxacillin volume of distribution

Probenecid decreases the apparent volume of distribution and slows the rate of excretion by competitively inhibiting renal tubular secretion of penicillin. Penicillin-probenecid therapy is generally limited to those infections where very high serum levels of penicillin are necessary.

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2018 Statistics

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What is Dicloxacillin

One of the penicillins which is resistant to penicillinase.

Dicloxacillin mechanism of action

Dicloxacillin exerts a bactericidal action against penicillin-susceptible microorganisms during the state of active multiplication. All penicillins inhibit the biosynthesis of the bacterial cell wall. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, dicloxacillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that dicloxacillin interferes with an autolysin inhibitor.

Dosage forms of Dicloxacillin

Capsuleoral250 mg/1
Capsuleoral500 mg/1

Prescription Generics


International Brands

Dicloxacillin Sodium


(2S,5R,6R)-6-({(3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl)carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid Dicloxacilina


Liberty Pharmaceuticals, Inc.

CAS number






Affected organisms

Enteric bacteria and other eubacteria

Indication of Dicloxacillin

Used to treat infections caused by penicillinase-producing staphylococci which have demonstrated susceptibility to the drug.

Toxicity of Dicloxacillin

Oral LD sub50 /sub in rat is 3579 mg/kg. Symptoms of overexposure include irritation, rash, labored breathing, hives, itching, wheezing, nausea, chills, and fever.

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