Save up -80% on Didanosine
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
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2019 Price of Videx
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Videx coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Didanosine every time. What are you waiting for? Claim your prescription drug card now!
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Didanosine volume of distribution
The apparent volume of distribution of didanosine following IV administration averages 1.08 l/kg in adult patient sand 28 l/sq m in pediatric patients. Didanosine is distributed into CSF following iv administration; CSF concentrations average 21% of concurrent plasma concentrations in samples obtained 1 hr after a dose of the drug. In one study in children and adolescents with symptomatic HIV infection who received a single oral dose or iv dose of didanosine, CSF concentrations were 46% (12-85%) of concurrent plasma concentrations.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Didanosine
A dideoxynucleoside compound in which the 3 #39;-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite.
Didanosine mechanism of action
Didanosine (ddI) is metabolized intracellularly by a series of cellular enzymes to its active moiety, dideoxyadenosine triphosphate (ddATP), which inhibits the HIV reverse transcriptase enzyme competitively by competing with natural dATP. It also acts as a chain terminator by its incorporation into viral DNA as the lack of a 3′-OH group in the incorporated nucleoside analogue prevents the formation of the 5′ to 3′ phosphodiester linkage essential for DNA chain elongation, and therefore, the viral DNA growth is terminated.
Dosage forms of Didanosine
|Videx EC||125mg||30 EC Capsule||$145.33|
|Videx EC||200mg||30 EC Capsule||$226.46|
|Videx EC||250mg||30 EC Capsule||$286.61|
|Videx EC||400mg||30 EC Capsule||$444.00|
|Didanosine||250mg||30 EC Capsule||$101.00|
|Didanosine||400mg||30 EC Capsule||$147.00|
State of Florida DOH Central Pharmacy
Human Immunodeficiency Virus
Indication of Didanosine
For use, in combination with other antiretroviral agents, in the treatment of HIV-1 infection in adults.
Toxicity of Didanosine
Side effects include pancreatitis, peripheral neuropathy, diarrhea, hyperuricemia and hepatic dysfunction
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