Save up -80% on Diethylpropion
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2018 Price of Diethylpropion
Diethylpropion HCl CR 75 mg 24 Hour tablet
* price without discount in nearest pharmacy. Price may vary.
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Diethylpropion volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Diethylpropion
A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Diethylpropion mechanism of action
Diethylpropion is an amphetamine that stimulates neurons to release or maintain high levels of a particular group of neurotransmitters known as catecholamines; these include dopamine and norepinephrine. High levels of these catecholamines tend to suppress hunger signals and appetite. Diethylpropion (through catecholamine elevation) may also indirectly affect leptin levels in the brain. It is theorized that diethylpropion can raise levels of leptin which signal satiety. It is also theorized that increased levels of the catecholamines are partially responsible for halting another chemical messenger known as neuropeptide Y. This peptide initiates eating, decreases energy expenditure, and increases fat storage.
Dosage forms of Diethylpropion
|Tablet, extended release||oral||75 mg/1|
Diethylpropion HCl Controlled-release
Preferred Pharmaceuticals, Inc.
Humans and other mammals
Indication of Diethylpropion
Used in the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction.
Toxicity of Diethylpropion
The reported oral LD sub 50 /sub for mice is 600 mg/kg, for rats is 250 mg/kg and for dogs is 225 mg/kg. Manifestation of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.
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