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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Florone

$158.51 tube (60g) 0.05% ointment
price without discount in nearest pharmacy. Price may vary.

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Diflorasone volume of distribution

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About RX24Drugs

2018 Statistics

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Discount Cards 16,000+

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Clients Benefit 29%

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Total savings $4,735,080

What is Diflorasone

Diflorasone is a topical corticosteroid used to treat itching and inflammation of the skin.

Diflorasone mechanism of action

The precise mechanism of the antiinflammatory activity of topical steroids in the treatment of steroid-responsive dermatoses, in general, is uncertain. However, corticosteroids are thought to act by the induction of phospholipase A sub 2 /sub inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A sub 2 /sub .

Dosage forms of Diflorasone

FormRouteStrength
Creamtopical.5 mg/g
Ointmenttopical.5 mg/g
Creamtopical.05 %

Prescription Generics

true

International Brands

Apexicon

Synonyms

(6alpha,11beta,16beta)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione (6,11,16)-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione

Manufacturers

PharmaDerm, A division of Nycomed US Inc.

CAS number

2557-49-5

UNII

T2DHJ9645W

State

solid

Affected organisms

Humans and other mammals

Indication of Diflorasone

For relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.

Toxicity of Diflorasone

Topically applied diflorasone can be absorbed in sufficient amounts to produce systemic effects. Symptoms of overdose include thinning of skin and suppression of adrenal cortex (decreased ability to respond to stress).

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