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Price of Diflorasone
Diflorasone 0.05% cream
* price without discount in nearest pharmacy. Price may vary.
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Diflorasone volume of distribution
What is Diflorasone
Diflorasone is a topical corticosteroid used to treat itching and inflammation of the skin.
Diflorasone mechanism of action
The precise mechanism of the antiinflammatory activity of topical steroids in the treatment of steroid-responsive dermatoses, in general, is uncertain. However, corticosteroids are thought to act by the induction of phospholipase A sub 2 /sub inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A sub 2 /sub .
Dosage forms of Diflorasone
PharmaDerm, A division of Nycomed US Inc.
Humans and other mammals
Indication of Diflorasone
For relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.
Toxicity of Diflorasone
Topically applied diflorasone can be absorbed in sufficient amounts to produce systemic effects. Symptoms of overdose include thinning of skin and suppression of adrenal cortex (decreased ability to respond to stress).
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