Save up -80% on Digitoxin
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2018 Price of Digitoxin
* price without discount in nearest pharmacy. Price may vary.
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Digitoxin volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Digitoxin
A cardiac glycoside sometimes used in place of digoxin. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. (From Martindale, The Extra Pharmacopoeia, 30th ed, p665)
Digitoxin mechanism of action
Digitoxin inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations. Increased intracellular concentrations of calcium may promote activation of contractile proteins (e.g., actin, myosin). Digitoxin also acts on the electrical activity of the heart, increasing the slope of phase 4 depolarization, shortening the action potential duration, and decreasing the maximal diastolic potential.
Dosage forms of Digitoxin
Digitaline Welcker Tab 0.1mg
Crystodigin (tn) Digitoksin
Welcker Lyster Ltd., Division Of Technilab Inc.
Humans and other mammals
Indication of Digitoxin
For the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
Toxicity of Digitoxin
Digitoxin exhibits similar toxic effects to the more-commonly used digoxin, namely: anorexia, nausea, vomiting, diarrhoea, confusion, visual disturbances, and cardiac arrhythmias.
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