Save up -80% on Dihydroergotamine

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
Pharmacists and Patients support.

2019 Price of D.H.E. 45

$1,531.951 nasal spray (8 vials) 4mg/ml
Price with discount in nearest pharmacy. Price may vary.

Claim your free Dihydroergotamine discount card

We offer free Dihydroergotamine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Dihydroergotamine every time. What are you waiting for? Claim your prescription drug card now!

Walgreens pharmacy
Walgreens pharmacy
CVS pharmacy
CVS pharmacy
Walmart pharmacy
Walmart pharmacy
Ride AID pharmacy
Ride AID pharmacy
CVS Target pharmacy
CVS Target pharmacy
Kroger pharmacy
Kroger pharmacy

Get your Prescription


It’s safe and free


Buy drugs in pharmacy

save money

Save money each time

Dihydroergotamine volume of distribution

Apparent volume of distribution is about 30 L/kg. The total body clearance is about 1.5 L/min., reflecting mainly the
hepatic clearance. Elimination from the plasma is biphasic with an a-phase of 1.5 hours and a ß-phase of 15 hours.

RX Prescription
Ask Your therapeut before taking any drugs.

About RX24Drugs

2018 Statistics

discount card

Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Dihydroergotamine

A 9,10alpha-dihydro derivative of ergotamine. It is used as a vasoconstrictor, specifically for the therapy of migraine disorders.

Dihydroergotamine mechanism of action

Two theories have been proposed to explain the efficacy of 5-HT sub 1D /sub receptor agonists in migraine: 1) activation of 5-HT sub 1D /sub receptors located on intracranial blood vessels, including those on arterio-venous anastomoses, leads to vasoconstriction, which correlates with the relief of migraine headache and 2) activation of 5-HT sub 1D /sub receptors on sensory nerve endings of the trigeminal system results in the inhibition of pro-inflammatory neuropeptide release.

Dosage forms of Dihydroergotamine

Liquidintramuscular; intravenous; subcutaneous1 mg
Injection, solutionintramuscular; intravenous; subcutaneous1 mg/mL
Spraynasal4 mg/mL

Prescription Generics


International Brands

D.H.E. 45


(2R,4R,7R)-N-((1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo(,6)dodecan-4-yl)-6-methyl-6,11-diazatetracyclo(,7.012,16)hexadeca-1(16),9,12,14-tetraene-4-carboxamide 5′-Benzyl-12′-hydroxy-2′-methyl-3′,6′,18-trioxo-9,10-dihydroergotaman


Valeant Pharmaceuticals North America

CAS number






Affected organisms

Humans and other mammals

Indication of Dihydroergotamine

For the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes.

Toxicity of Dihydroergotamine

Side effects include abdominal pain, abnormal speech, coma, confusion, convulsions, hallucinations, increase and/or decrease in blood pressure, nausea, numbness, tingling, pain, and a bluish color of your fingersand toes, slowed breathing, vomiting

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Dihydroergotamine on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

Get lower price on Dihydroergotamine now!