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Price of Diltiazem
Diltiazem 90 mg tablet
* price without discount in nearest pharmacy. Price may vary.
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Diltiazem volume of distribution
What is Diltiazem
A benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions. It is also teratogenic. (PubChem)
Diltiazem mechanism of action
Possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum, diltiazem, like verapamil, inhibits the influx of extracellular calcium across both the myocardial and vascular smooth muscle cell membranes. The resultant inhibition of the contractile processes of the myocardial smooth muscle cells leads to dilation of the coronary and systemic arteries and improved oxygen delivery to the myocardial tissue.
Dosage forms of Diltiazem
|Capsule (controlled-delivery)||oral||120 mg|
|Capsule (controlled-delivery)||oral||180 mg|
|Capsule (controlled-delivery)||oral||240 mg|
Act Diltiazem CD
(+)-cis-5-(2-(dimethylamino)Ethyl)-2,3-dihydro-3-hydroxy-2-(P-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate ester
Actavis Pharma Company
Humans and other mammals
Indication of Diltiazem
For the treatment of Hypertension
Toxicity of Diltiazem
LD sub 50 /sub =740mg/kg (orally in mice)
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