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2018 Price of Dimenhydrinate
Dimenhydrinate I.M. 50 mg/ml
ml
* price without discount in nearest pharmacy. Price may vary.
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Dimenhydrinate volume of distribution
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What is Dimenhydrinate
Dimenhydrinate (Dramamine, Gravol and Vertirosan) is an over-the-counter drug used to prevent motion sickness. It is closely related to diphenhydramine HCl, or Benadryl. It is primarily a H1-antagonist, but also possesses an antimuscarinic effect.
Dimenhydrinate mechanism of action
The mechanism by which some antihistamines exert their antiemetic, antindash;motion sickness, and antivertigo effects is not precisely known but may be related to their central anticholinergic actions. They diminish vestibular stimulation and depress labyrinthine function. An action on the medullary chemoreceptive trigger zone may also be involved in the antiemetic effect. Dimenhydrinate is a competitive antagonist at the histamine H1 receptor, which is widely distributed in the human brain. Dimenhydrinate’s anti-emetic effect is probably due to H1 antagonism in the vestibular system in the brain.
Dosage forms of Dimenhydrinate
| Form | Route | Strength |
|---|---|---|
| Tablet | oral | 25 mg/1 |
| Liquid | oral | 15 mg |
| Injection, solution | intramuscular; intravenous | 50 mg/mL |
Prescription Generics
false
International Brands
Airmit Ace
Synonyms
(O-Benzhydryl(dimethylamino)ethanol) 8-chlorotheophyllinate 8-chloro-1,3-Dimethyl-3,7-dihydro-1H-purine-2,6-dione – 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1)
Manufacturers
Sato Pharmaceutical Co., Ltd.
CAS number
523-87-5
UNII
JB937PER5C
State
solid
Affected organisms
Humans and other mammals
Indication of Dimenhydrinate
Used for treating vertigo, motion sickness, and nausea associated with pregnancy.
Toxicity of Dimenhydrinate
Symptoms of overdose include delerium, hallucinations, and excitment. Patients may be violent and confused.
RX24 Drugs Disclaimer: before buying a Dimenhydrinate on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.
