Save up -80% on Dimethyl fumarate
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Tecfidera
|$7,906.77||1 dose pack (60 capsules) 240mg|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Dimethyl fumarate coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Dimethyl fumarate every time. What are you waiting for? Claim your prescription drug card now!
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Dimethyl fumarate volume of distribution
In healthy people, MMF has a variable volume of distribution of 53 to 73 litres.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Dimethyl fumarate
Dimethyl fumarate is an anti-inflammatory. It is indicated for multiple sclerosis patients with relapsing forms and is also being investigated for the treatment of psoriasis. The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood. It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway that is activated in response to oxidative stress. Dimethyl fumarate is marketed under the brand name Tecfidera.
Dimethyl fumarate mechanism of action
The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood. It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF). MMF up-regulates the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway that is activated in response to oxidative stress. As well MMF is an agonist at the nicotinic acid receptor, but the relevance of this is not known.
Dosage forms of Dimethyl fumarate
(e)-But-2-enedioic acid dimethyl ester 1,2-Bis(methoxycarbonyl)-trans-ethylene
Humans and other mammals
Indication of Dimethyl fumarate
Used in multiple sclerosis patients with relapsing forms.
Toxicity of Dimethyl fumarate
The most common side effects observed were nausea, diarrhea, abdominal pain, and flushing.
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