Save up -80% on Dipyridamole
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Persantine
|$31.09||60 tablets/75 mg|
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Dipyridamole coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Dipyridamole every time. What are you waiting for? Claim your prescription drug card now!
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Dipyridamole volume of distribution
* 1 to 2.5 L/kg
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Dipyridamole
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Dipyridamole mechanism of action
Dipyridamole likely inhibits both adenosine deaminase and phosphodiesterase, preventing the degradation of cAMP, an inhibitor of platelet function. This elevation in cAMP blocks the release of arachidonic acid from membrane phospholipids and reduces thromboxane A2 activity. Dipyridamole also directly stimulates the release of prostacyclin, which induces adenylate cyclase activity, thereby raising the intraplatelet concentration of cAMP and further inhibiting platelet aggregation.
Dosage forms of Dipyridamole
|Dipyridamole/Asa||200/25mg||100 ER Capsule||$18.35|
Cardoxin Cleridium 150
Rebel Distributors Corp.
Humans and other mammals
Indication of Dipyridamole
For as an adjunct to coumarin anticoagulants in the prevention of postoperative thromboembolic complications of cardiac valve replacement and also used in prevention of angina.
Toxicity of Dipyridamole
Hypotension, if it occurs, is likely to be of short duration, but a vasopressor drug may be used if necessary. The oral LD sub 50 /sub in rats is greater than 6,000 mg/kg while in the dogs, the oral LD sub 50 /sub is approximately 400 mg/kg. LD sub 50 /sub =8.4g/kg (orally in rat)
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