Save up -80% on Disopyramide
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
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2019 Price of Norpace
|price without discount in nearest pharmacy. Price may vary.|
We offer free Norpace coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Disopyramide every time. What are you waiting for? Claim your prescription drug card now!
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Disopyramide volume of distribution
The protein binding (50% to 60%) and volume of distribution (<1 L/kg) of disopyramide are less than those of quinidine or procainamide and suggest the possibility that hemodialysis could be effective in removing toxic concentrations.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Disopyramide
A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
Disopyramide mechanism of action
Disopyramide is a Type 1A antiarrhythmic drug (ie, similar to procainamide and quinidine). It inhibits the fast sodium channels. In animal studies Disopyramide decreases the rate of diastolic depolarization (phase 4) in cells with augmented automaticity, decreases the upstroke velocity (phase 0) and increases the action potential duration of normal cardiac cells, decreases the disparity in refractoriness between infarcted and adjacent normally perfused myocardium, and has no effect on alpha- or beta-adrenergic receptors.
Dosage forms of Disopyramide
Mayne Pharma Inc.
Humans and other mammals
Indication of Disopyramide
For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias. It is a Class Ia antiarrhythmic drug.
Toxicity of Disopyramide
LD sub 50 /sub =580 mg/kg in rats
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