Save up -80% on Dolutegravir

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Tivicay

$172.7514 tablets/10 mg
Price with discount in nearest pharmacy. Price may vary.

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We offer free Tivicay coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Dolutegravir every time. What are you waiting for? Claim your prescription drug card now!

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Dolutegravir volume of distribution

Volume of distribution (Vd/F), 50 mg once daily = 17.4 L. The median dolutegravir concentration in the CSF was 18 ng/mL after 2 weeks of treatment.

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2018 Statistics

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Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Dolutegravir

Dolutegravir is indicated for HIV-1 infection for adults and children and adolescents 12 years of age and weighing 40 kg. It is marketed as Tivicay as dolutegravir sodium. 52.6 mg of dolutegravir sodium is equivalent to 50 mg dolutegravir free acid. FDA approved on August 12, 2013.

Dolutegravir mechanism of action

Dolutegravir is an HIV-1 antiviral agent. It inhibits HIV integrase by binding to the active site and blocking the strand transfer step to retroviral DNA integration. This is an essential step of the HIV replication cycle and will result in an inhibition of viral activity. Dolutegravir has a mean EC50 value of 0.5 nM (0.21 ng/mL) to 2.1 nM (0.85 ng/mL) in peripheral blood mononuclear cells (PBMCs) and MT-4 cells.

Dosage forms of Dolutegravir

DrugDosageQuantityPrice
Tivicay10mg30 tabletes$347.65
Tivicay25mg30 tabletes$854.88
Tivicay50mg90 tabletes$4,904

Prescription Generics

false

International Brands

Tivicay

Synonyms

Manufacturers

Vii V Healthcare Company

CAS number

1051375-16-6

UNII

DKO1W9H7M1

State

solid

Affected organisms

Human Immunodeficiency Virus

Indication of Dolutegravir

Dolutegravir is indicated in combination with other antiretroviral agents for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults and children aged 12 years and older and weighing at least 40 kg.

Toxicity of Dolutegravir

The most common adverse reactions of moderate to severe intensity and incidence 2% (in those receiving TIVICAY in any one adult trial) are insomnia and headache.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Dolutegravir on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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