Save up -80% on Dolutegravir
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Tivicay
|$172.75||14 tablets/10 mg|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Tivicay coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Dolutegravir every time. What are you waiting for? Claim your prescription drug card now!
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Dolutegravir volume of distribution
Volume of distribution (Vd/F), 50 mg once daily = 17.4 L. The median dolutegravir concentration in the CSF was 18 ng/mL after 2 weeks of treatment.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Dolutegravir
Dolutegravir is indicated for HIV-1 infection for adults and children and adolescents 12 years of age and weighing 40 kg. It is marketed as Tivicay as dolutegravir sodium. 52.6 mg of dolutegravir sodium is equivalent to 50 mg dolutegravir free acid. FDA approved on August 12, 2013.
Dolutegravir mechanism of action
Dolutegravir is an HIV-1 antiviral agent. It inhibits HIV integrase by binding to the active site and blocking the strand transfer step to retroviral DNA integration. This is an essential step of the HIV replication cycle and will result in an inhibition of viral activity. Dolutegravir has a mean EC50 value of 0.5 nM (0.21 ng/mL) to 2.1 nM (0.85 ng/mL) in peripheral blood mononuclear cells (PBMCs) and MT-4 cells.
Dosage forms of Dolutegravir
Vii V Healthcare Company
Human Immunodeficiency Virus
Indication of Dolutegravir
Dolutegravir is indicated in combination with other antiretroviral agents for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults and children aged 12 years and older and weighing at least 40 kg.
Toxicity of Dolutegravir
The most common adverse reactions of moderate to severe intensity and incidence 2% (in those receiving TIVICAY in any one adult trial) are insomnia and headache.
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