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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Dopamine

Dopamine 400 mg-d5w 250 ml

$0.04

ml

* price without discount in nearest pharmacy. Price may vary.

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Dopamine volume of distribution

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What is Dopamine

One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.

Dopamine mechanism of action

Dopamine is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system. Dopamine produces positive chronotropic and inotropic effects on the myocardium, resulting in increased heart rate and cardiac contractility. This is accomplished directly by exerting an agonist action on beta-adrenoceptors and indirectly by causing release of norepinephrine from storage sites in sympathetic nerve endings. In the brain, dopamine actas as an agonist to the five dopamine receptor subtypes (D!, D2, D3, D4, D5).

Dosage forms of Dopamine

FormRouteStrength
Injection, solutionintravenous160 mg/mL
Injection, solutionintravenous40 mg/mL
Injection, solutionintravenous80 mg/mL
Prescription Generics

true

International Brands

Dopamine

Synonyms

2-(3,4-Dihydroxyphenyl)ethylamine 3-Hydroxytyramine

Manufacturers

General Injectables Vaccines, Inc

CAS number

51-61-6

UNII

VTD58H1Z2X

State

solid

Affected organisms

Humans and other mammals

Indication of Dopamine

For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure

Toxicity of Dopamine

LD sub 50 /sub oral mice = 1460 mg/kg, LD sub 50 /sub oral rats = 1780 mg/kg. Spasm or closing of eyelids, nausea, vomiting, cardiac arrhythmias, involuntary movements of the body including the face, tongue, arms, hand, head, and upper body; hypotension, haemolytic anaemia, urinary retention, duodenal ulcer, sialorrhea, ataxia, abdominal pain, dry mouth, nightmares, tachypnoea, bruxism, confusion, and insomnia.

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