Save up -80% on Doxapram
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Price of Doxapram
Dopram 20 mg/ml vial
* price without discount in nearest pharmacy. Price may vary.
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Doxapram volume of distribution
What is Doxapram
A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Doxapram mechanism of action
Doxapram produces respiratory stimulation mediated through the peripheral carotid chemoreceptors. It is thought to stimulate the carotid body by inhibiting certain potassium channels.
Dosage forms of Doxapram
West Ward Pharmaceutical Corp.
Humans and other mammals
Indication of Doxapram
For use as a temporary measure in hospitalized patients with acute respiratory insufficiency superimposed on chronic obstructive pulmonary disease.
Toxicity of Doxapram
Intravenous LD sub50 /sub values in the mouse and rat were approximately 75 mg/kg and in the cat and dog were 40 to 80 mg/kg. Symptoms of overdosage are extensions of the pharmacologic effects of the drug. Excessive pressor effect, tachycardia, skeletal muscle hyperactivity, and enhanced deep tendon reflexes may be early signs of overdosage.
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