Save up -80% on Doxazosin
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Cardura
|price without discount in nearest pharmacy. Price may vary.|
We offer free Cardura coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Doxazosin every time. What are you waiting for? Claim your prescription drug card now!
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Doxazosin volume of distribution
Protein binding is reported to be 98.3% in humans. Relatively low clearance (1.0 to 2.0 ml/min/kg) in association with a moderate volume of distribution (1.0 to 1.9 liters/kg) is responsible for doxazosin’s relatively long plasma half-life.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Doxazosin
Doxazosin is a quinazoline-derivative that selectively antagonizes postsynaptic alpha; sub1 /sub-adrenergic receptors. It may be used to mild to moderate hypertension and in the management of symptomatic benign prostatic hyperplasia (BPH). alpha; sub1 /sub-Receptors mediate contraction and hypertrophic growth of smooth muscle cells. Antagonism of these receptors leads to smooth muscle relaxation in the peripheral vasculature and prostate gland.
Doxazosin mechanism of action
Doxazosin acts by inhibiting the postsynaptic alpha(1)-adrenoceptors on vascular smooth muscle. This inhibits the vasoconstrictor effect of circulating and locally released catecholamines (epinephrine and norepinephrine), resulting in peripheral vasodilation.
Dosage forms of Doxazosin
|Cardura XL||4mg||90 Tablet||$110.00|
|Cardura XL||8mg||90 ER Tablet||$160.00|
Humans and other mammals
Indication of Doxazosin
For treatment and management of mild to moderate hypertension and urinary obstruction symptoms caused by BPH.
Toxicity of Doxazosin
Symptoms of overdose include hypotension. Oral LD sub50 /sub is greater than 1000 mg/kg in mice and rats.
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